Sasha with his sister-donor Nastia

Our family, the Novokreschenovs, lives in Kostomuksha, a town in the republic of Karelia. We have two children, ten-year-old Nastia, our daughter, and Sasha, our son, who was born on March 29, 2005. In fall 2007 we started applying for his daycare admission. Not long before that we noticed that Sasha was slightly limping in the right leg, which developed small bruises. He also started to get tired easily. Sasha's blood tests turned out to be abnormal, and the doctors diagnosed him with acute leukemia.
Sasha and I were referred to the Hematology unit at the Republican hospital in Petrozavodsk. My husband took Sasha's blood and marrow samples to St. Petersburg Pavlov Medical University several times. A more accurate diagnosis was set there: biphenotypical leukemia. With this kind of leukemia bone marrow transplantation is always recommended.
In Petrozavodsk Sasha underwent two chemotherapy blocks within four months. After that he achieved remission. The testing showed that his older sister Nastia is a suitable bone marrow donor for Sasha.
The transplantation is scheduled for February 26, 2008. It will take place in Pavlov Medical University. Due to the transplantation, we have significant upcoming expenses, such as apartment rent near the university, partial pay for the medical tests, and living expenses several months.
We will be grateful to everyone who helps us!

Irina and Mikhail Novokreschenov
Contact phones:
+7 (911) 908-38-61 (Mikhail)
+7 (921) 227-54-74 (Irina and Mikhail)

Medical conclusion

Update as of March 4, 2008. It has been a week since Sasha's transplantation. Everything is proceeding as planned. The doctors allowed Sasha's sister, his donor, to go home to Kostomuksha. Sasha is still in cytopenia, but feels relatively well.

Update as of March 26, 2008. Sasha recovered after transplantation and was discharged for outpatient monitoring. He lives at a rented apartment and feels relatively well.

Update as of April 4, 2008. We are sincerely grateful to Russian Help Fund for buying 7 packages of Vfend (50 mg) and 6.5 packages at 200 mg dosage for Sasha for the total of 250,449 rubles.

Update as of April 18, 2008. Sasha completed planned examination. The test results are normal and he feels well.

Update as of July 6, 2008. Sasha's percentage of donated bone marrow had dropped. His sister who was a donor was called in. Sasha is planned to receive donated lymphocytes.

Update as of July 24, 2008. Today Sasha had a puncture and the results should be ready either tomorrow or on Monday. Two weeks ago he had the first donor lymphocyte infusion. His doctor Natalia Vassilievna told us that Sasha will need several infusions.
Sasha's father

Update as of August 3, 2008. Based on the test results, percentage of donor’s bone marrow grew from 50% to 70% after infusion of donor’s lymphocytes. Two more infusions are planned.

Update as of August 26, 2008. Sasha is now being monitored by the doctors, as his bone marrow engraftment indicators dropped. He is planned to undergo donor lymphocyte infusion from his sister.

Update as of October 4, 2008. Sasha had lymphocyte infusion again. The percentage of the donor's bone marrow started to grow again. Sasha feels well and grew up quite a bit. He is also starting to talk.

Update as of October 31, 2008. Sasha's condition stabilized. On November 12th he will return home to be monitored by the hematologists in Petrozavodsk.

Update as of November 11, 2008. Sasha completed treatment and returned home.

Update as of November 25, 2008. Our trip home was good. Sasha really missed his sister Nastia. Now our home is always noisy and the toys are spread all over the place, but it feels so good!
We are very grateful to everyone who has been helping us!
Sasha and Irina Novokreschenov

Update as of December 25, 2008. Sasha came for planned testing. The puncture results show that the donor's cell content grew to 80%. Sasha feels well. His liver indicators are a little elevated.

Update as of January 11, 2009. New Sasha's photos

Update as of April 14, 2009 Sasha came for examinations. The results are good, the boy is feeling fine.

Update as of August 19, 2009 Thank God, we are doing well. I am sending a few new pictures.
Respectfully,
Mikhail, Sasha's dad

Update as of October 3, 2009 Sasha had a relapse. He is now undergoing chemotherapy under FLAG protocol in St. Petersburg. Further treatment will be discussed once the results are available.

Update as of October 26, 2009. Unfortunately, Sasha was not able to achieve remission. A decision was made to offer Sasha second transplantation. Nastia, Sasha's sister, who will be his donor, will travel to St. Petersburg for tests, and if everything is well, the conditioning regiment will start after 10 days. Sasha's family urgently needs financial support for living expenses.

Update as of October 26, 2009. Sasha is still receiving anti-relapse chemotherapy. Unfortunately, he also got fungal infection in addition to other complications. Sasha receives Fungizone therapy.

Update as of December 24, 2009. Sasha has recovered after the transplantation. Based on the computed tomography results he was prescribed Vfend.

Update as of January 19, 2010. Sasha fully recovered after transplantation, but since the doctors feel that it may not be sustained, he receives immunotherapy with lymphocytes, interferon, and GM-CSF (colony-stimulating factor) to prevent relapse.

Update as of February 20, 2010. Sasha is soon to start a 3-months' immunotherapy course with Roferon and Neostim. Please help us buy Neostim. Sasha needs 3 vials per week, each one costs 3,500 roubles.

Update as of March 3, 2010. Sasha is in remission. The course of treatment with Roferon and Neostim will last two more months.

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